To fuse or not to fuse: how do checkpoint and DNA repair proteins maintain telomeres?
نویسندگان
چکیده
منابع مشابه
To fuse or not to fuse: how do checkpoint and DNA repair proteins maintain telomeres?
DNA damage checkpoint and DNA repair mechanisms play critical roles in the stable maintenance of genetic information. Various forms of DNA damage that arise inside cells due to common errors in normal cellular processes, such as DNA replication, or due to exposure to various DNA damaging agents, must be quickly detected and repaired by checkpoint signaling and repair factors. Telomeres, the nat...
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Since the dawn of time, or at least the dawn of recombinant DNA technology (which for many of today's scientists is the same thing), investigators have been cloning and expressing heterologous proteins in a variety of different cells for a variety of different reasons. These range from cell biological studies looking at protein-protein interactions, post-translational modifications, and regulat...
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Many cells are able to orient themselves in a non-uniform environment by responding to localized cues. This leads to a polarized cellular response, where the cell can either grow or move towards the cue source. Fungal haploid cells secrete pheromones to signal mating, and respond by growing a mating projection towards a potential mate. Upon contact of the two partner cells, these fuse to form a...
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ژورنال
عنوان ژورنال: Frontiers in Bioscience
سال: 2010
ISSN: 1093-9946,1093-4715
DOI: 10.2741/3664